Rutin (Quercetin-3-rutinoside)
Rutin is a flavonoid glycoside of quercetin with anti-thrombotic, anti-inflammatory, and vascular-protective properties, commonly used for venous insufficiency and edema reduction.
cardiovascularanti thromboticanti inflammatoryantioxidant
Evidence last reviewed: 20 Apr 2026
Evidence
3 records3 recordsBest grade:Moderate
Moderate evidence suggests that rutin may help reduce symptoms of chronic venous insufficiency and edema. While the findings are promising, more high-quality studies are needed to strengthen the conclusions.
Venous insufficiency symptomsPatients with chronic venous insufficiency · Systematic reviewModerate
Venous insufficiency symptoms
Patients with chronic venous insufficiency · Systematic review
Phlebotonics, including rutosides, probably reduce edema slightly compared to placebo.
Dose: 500 mg
Moderate-certainty evidence suggests slight reduction in edema.
Post-thrombotic syndrome preventionPatients with chronic venous insufficiency · Systematic reviewModerate
Post-thrombotic syndrome prevention
Patients with chronic venous insufficiency · Systematic review
Venoactive compounds are recommended for prevention and treatment of post-thrombotic syndrome.
Dose: 500 mg
Evidence supports use in post-thrombotic syndrome.
Edema reductionPatients with chronic venous insufficiency · RCTModerate
Edema reduction
Patients with chronic venous insufficiency · RCT
Moderate-certainty evidence suggests phlebotonics reduce edema slightly compared to placebo.
Dose: 500 mg
Study focused on edema prevention during flights.
Stacks containing Rutin (Quercetin-3-rutinoside)
Explore all →No public stacks include this supplement yet.
Community Insights
Forms & usage▾
How to take it
Take 500-1000 mg daily, preferably with meals.
Capsule
Commonly available in 500 mg doses.
Tablet
Often used for standardized dosing.
Powder
Can be mixed with liquids for easier consumption.
My notes▾
Sign in to keep a private note on Rutin (Quercetin-3-rutinoside).