StackTerminal.Health

StackTerminal.Health

Rutin (Quercetin-3-rutinoside)

Rutin is a flavonoid glycoside of quercetin with anti-thrombotic, anti-inflammatory, and vascular-protective properties, commonly used for venous insufficiency and edema reduction.

cardiovascularanti thromboticanti inflammatoryantioxidant

Evidence last reviewed: 20 Apr 2026

Buy← Back
Who should avoid this
  • •pregnant or breastfeeding individuals
  • •those with known allergies to flavonoids
  • •people on anticoagulant medications
Evidence
3 records
3 recordsBest grade:Moderate

Moderate evidence suggests that rutin may help reduce symptoms of chronic venous insufficiency and edema. While the findings are promising, more high-quality studies are needed to strengthen the conclusions.

Venous insufficiency symptoms
Patients with chronic venous insufficiency · Systematic review
Moderate

Phlebotonics, including rutosides, probably reduce edema slightly compared to placebo.

Dose: 500 mg
Citation: Perera et al. (2012). Phlebotonics for haemorrhoids. Journal.
Moderate-certainty evidence suggests slight reduction in edema.
Post-thrombotic syndrome prevention
Patients with chronic venous insufficiency · Systematic review
Moderate

Venoactive compounds are recommended for prevention and treatment of post-thrombotic syndrome.

Dose: 500 mg
Citation: Gloviczki et al. (2025). Utility of venoactive compounds in post-thrombotic syndrome: A systematic review. Journal.
Evidence supports use in post-thrombotic syndrome.
Edema reduction
Patients with chronic venous insufficiency · RCT
Moderate

Moderate-certainty evidence suggests phlebotonics reduce edema slightly compared to placebo.

Dose: 500 mg
Citation: Cesarone et al. (2002). Flight microangiopathy in medium-to-long distance flights: prevention of edema and microcirculation alterations with HR (Paroven, Venoruton; 0-(beta-hydroxyethyl)-rutosides): a prospective, randomized, controlled trial. Journal.
Study focused on edema prevention during flights.
Stacks containing Rutin (Quercetin-3-rutinoside)
Explore all →
No public stacks include this supplement yet.
Community Insights
Forms & usage▾
How to take it

Take 500-1000 mg daily, preferably with meals.

Capsule
Commonly available in 500 mg doses.
Tablet
Often used for standardized dosing.
Powder
Can be mixed with liquids for easier consumption.
My notes▾
Sign in to keep a private note on Rutin (Quercetin-3-rutinoside).
Sign in