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Red Light / Near-Infrared Therapy (Photobiomodulation)

Red light and near-infrared therapy, also known as photobiomodulation, is used to enhance mitochondrial function and reduce oxidative stress, with evidence supporting its use for wound healing, pain reduction, skin rejuvenation, and cognitive performance.

recoveryanti inflammatoryskin healthcognitive

Evidence last reviewed: 20 Apr 2026

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Evidence
5 records
5 recordsBest grade:Moderate
Biomarkers
Cognitive FunctionMuscle EnduranceRecovery Score

The evidence base is moderate, showing effectiveness in cognitive function, pain reduction, wound healing, and skin rejuvenation. However, the strength of evidence for sports performance is low, indicating a need for further research in that area.

Skin rejuvenation
General population · Systematic review
Moderate

Red and near-infrared light therapy is effective for skin rejuvenation, including treatment of acne and alopecia.

Dose: —
Citation: Salehpour et al. (2020). Photobiomodulation for Parkinson's Disease in Animal Models: A Systematic Review.
Wound healing
General population · Systematic review
Moderate

Photobiomodulation has been shown to improve wound healing and reduce inflammation.

Dose: —
Citation: Xie et al. (2023). A systematic review of the effect of photobiomodulation on the neuroinflammatory response in animal models of neurodegenerative diseases.
Cognitive function
Healthy adults and those with cognitive disorders · Systematic review
Moderate

Transcranial photobiomodulation has shown positive improvements in cognitive functions, including memory and attention.

Dose: —Form: LED
Citation: Santos et al. (2018). Effects of transcranial LED therapy on the cognitive rehabilitation for diffuse axonal injury due to severe acute traumatic brain injury: study protocol for a randomized controlled trial.
Pain reduction
General population · Systematic review
Moderate

Photobiomodulation is effective in reducing pain and inflammation.

Dose: —
Citation: Xie et al. (2023). A systematic review of the effect of photobiomodulation on the neuroinflammatory response in animal models of neurodegenerative diseases.
Sports performance
Athletes · Systematic review
Low

Photobiomodulation may enhance sports performance by improving muscle recovery and reducing fatigue.

Dose: —Timing: preconditioning before exercise
Citation: Shetty et al. (2023). Effect of transcranial photobiomodulation on electrophysiological activity of brain in healthy individuals: A scoping review.
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Community Insights
Forms & usage▾
How to take it

Use a red light device for 10-20 minutes daily, targeting specific areas.

LED
Commonly used for home devices and skin treatments.
Laser
Used in clinical settings for targeted therapy.
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