StackTerminal.Health

BETA

Lumbrokinase

Lumbrokinase is an enzyme complex derived from earthworms, known for its thrombolytic & anti-aggregation effects, potentially benefiting individuals with ischemic stroke & cardiovascular conditions.

cardiovascularanti thromboticanti inflammatory

Evidence last reviewed: 05 Apr 2026

Evidence
3 records
3 recordsBest grade:Low

The evidence for lumbrokinase is primarily based on low-quality randomized controlled trials. While it shows potential benefits for stroke treatment and prevention, the overall strength of the evidence is weak and further studies are needed.

Efficacy in acute ischemic stroke
Patients with acute ischemic stroke · RCT
Low

The study aims to compare the efficacy of lumbrokinase plus aspirin versus aspirin alone in treating acute ischemic stroke.

Dose: 40 mgDuration: 90 days
Study protocol for a multicenter RCT.
Safety & tolerability
Healthy adult subjects · RCT
Low

The study evaluates the safety & tolerability of lumbrokinase in healthy adults.

Dose: 40 mgDuration: 180 days
Focus on safety & tolerability in a healthy population.
Secondary ischemic stroke prevention
Patients with a history of ischemic stroke · RCT
Low

The trial investigates the efficacy of lumbrokinase plus aspirin for secondary prevention of ischemic stroke.

Dose: 40 mg
Focus on secondary prevention of ischemic stroke.
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Forms & usage
How to take it

Typically taken as a capsule or tablet, follow dosing instructions on the product label.

Capsule
Commonly available in capsule form for oral administration.
Tablet
Available in tablet form, often combined with other supplements.
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