Lithium Orotate
Lithium Orotate is a lower-dose lithium salt used as a dietary supplement, potentially offering mood stabilization & neuroprotective benefits based on epidemiological data.
Evidence last reviewed: 05 Apr 2026
- •pregnant or breastfeeding individuals
- •those with kidney issues
- •people on certain medications
The evidence for Lithium Orotate is very low, primarily based on anecdotal reports and epidemiological data. While some studies suggest potential benefits for mood stabilization and neuroprotection, the lack of robust clinical trials limits confidence in its effectiveness.
NeuroprotectionGeneral population · Case seriesVery low
Potential neuroprotective effects are suggested by epidemiological data linking lithium in water to lower dementia rates.
Suicide rate reductionGeneral population · Case seriesVery low
Epidemiological data suggest lower suicide rates in areas with higher lithium levels in water.
Mood stabilizationGeneral population · Case seriesVery low
Lithium orotate may help stabilize mood based on anecdotal & theoretical evidence.
Forms & usage▾
Take 5-20 mg daily, preferably with food.