StackTerminal.Health

BETA

Lithium Orotate

Lithium Orotate is a lower-dose lithium salt used as a dietary supplement, potentially offering mood stabilization & neuroprotective benefits based on epidemiological data.

mental healthmoodneuroprotectionanti aging

Evidence last reviewed: 05 Apr 2026

Evidence
3 records
3 recordsBest grade:Very low
Biomarkers
Neuroprotection / NGFMood / Wellbeing

The evidence for Lithium Orotate is very low, primarily based on anecdotal reports and epidemiological data. While some studies suggest potential benefits for mood stabilization and neuroprotection, the lack of robust clinical trials limits confidence in its effectiveness.

Neuroprotection
General population · Case series
Very low

Potential neuroprotective effects are suggested by epidemiological data linking lithium in water to lower dementia rates.

Dose: 5 mgForm: Orotate
Based on epidemiological observations.
Suicide rate reduction
General population · Case series
Very low

Epidemiological data suggest lower suicide rates in areas with higher lithium levels in water.

Dose: 5 mgForm: Orotate
Based on epidemiological observations.
Mood stabilization
General population · Case series
Very low

Lithium orotate may help stabilize mood based on anecdotal & theoretical evidence.

Dose: 5 mgForm: Orotate
Based on theoretical & anecdotal evidence.
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Forms & usage
How to take it

Take 5-20 mg daily, preferably with food.

Orotate
Commonly used in dietary supplements for mood stabilization.
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