Hyaluronic Acid
Hyaluronic Acid is a naturally occurring substance that provides joint lubrication and skin hydration. It is commonly used to reduce knee pain and improve skin hydration, elasticity, and wrinkle depth.
Evidence last reviewed: 20 Apr 2026
The evidence supports Hyaluronic Acid's effectiveness for skin hydration and knee pain reduction, with moderate quality systematic reviews backing these claims. However, its benefits for vaginal atrophy in postmenopausal women are less robust, indicating a need for further research.
Skin hydration and elasticityGeneral population · Systematic reviewModerate
Hyaluronic acid is effective in improving skin hydration and elasticity.
Vaginal atrophy improvementPostmenopausal women · Systematic reviewLow
Hyaluronic acid was reported to improve symptoms of vaginal atrophy in postmenopausal women.
Knee pain reductionPatients with knee osteoarthritis · Systematic reviewModerate
Hyaluronic acid injections were found to improve WOMAC and VAS scores, indicating reduced pain and improved function.
Combining Hyaluronic Acid with Cat's Claw can support joint health and reduce inflammation. Hyaluronic Acid is known for its joint-lubricating properties, while Cat's Claw provides anti-inflammatory and immune support.
Forms & usage▾
Take 100-200 mg daily, preferably with water.