GHK-Cu (Copper Peptide)
GHK-Cu is a naturally occurring tripeptide-copper complex that supports collagen synthesis, wound healing, and hair growth, primarily used for anti-aging and skin health.
Evidence last reviewed: 13 May 2026
Not a routine supplement — not recommended for self-directed use.
Information here is educational only, not a recommendation to use. See our Safety page.
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Evidence is from research or clinical settings — does not imply safety outside supervised contexts.
The evidence for GHK-Cu includes a few randomized controlled trials showing potential benefits for wound healing and skin appearance, but the overall strength is low. There is a theoretical basis for collagen synthesis enhancement, but more robust studies are needed to confirm its efficacy.
Wound healingPatients with CO2 laser-resurfaced skin · RCTLow
GHK-Cu showed improvement in skin appearance and reduction in erythema post-treatment.
Wound healingPatients with venous stasis ulcers · RCTLow
GHK-Cu was associated with improved wound healing and skin appearance.
Collagen synthesisGeneral population · Case seriesVery low
GHK-Cu is theorized to enhance collagen synthesis based on its biochemical properties.