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BETA

DHEA

Endogenous adrenal hormone precursor that declines with age; supplementation evidence mostly in older adults for bone density & well-being.

hormoneslongevitydaily

Evidence last reviewed: 04 Apr 2026

Evidence
1 record
1 recordBest grade:Moderate

Research shows moderate evidence for DHEA's benefits in bone density and well-being among older adults, particularly postmenopausal women. However, the effects in younger populations are not well supported, and the potential for hormonal disruption raises concerns.

Bone density / well-being in older adults
Adults over 50; postmenopausal women · RCTs
Moderate

Modest improvement in bone density & quality of life in older adults; effects in younger adults not well supported.

Dose: 50 mgDuration: 12–24 months
A controlled substance in some countries; not for use under 30 unless deficiency confirmed.
Stacks containing DHEA
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hormonalenergymens-health

DHEA & maca root are combined to support hormonal balance & enhance energy levels. DHEA is a precursor to sex hormones that supports hormonal health, while maca root enhances energy & supports hormonal balance.

DHEA
50mg
Maca Root
1500mg
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Forms & usage
How to take it

Typical doses range from 25 to 50 mg daily, taken in the morning. Consult a healthcare provider for personalized dosing.

DHEA capsule (25–50 mg)
7-keto DHEA is a non-hormonal metabolite variant.
Safety & trade-offs4
Hormones

Converts to both estrogen and testosterone — can disrupt hormonal balance; women especially vulnerable to androgenic side effects

Note

May promote hormone-sensitive cancer growth (breast, prostate) — contraindicated with personal or family history

Hormones

Suppresses endogenous DHEA production with prolonged use

Note

Banned by WADA and most major sports bodies

High  Moderate   Low / note

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