StackTerminal.Health

BETA

Casein Protein

Casein protein is a slow-digesting milk protein that releases amino acids over several hours, making it effective for reducing overnight muscle protein breakdown. It is particularly beneficial for athletes and individuals engaging in resistance training when taken before sleep.

muscle growthrecoverysleepnutritional

Evidence last reviewed: 20 Apr 2026

Evidence
4 records
4 recordsBest grade:High
Biomarkers
Power OutputMuscle Strength (1RM)Muscle EnduranceRecovery Score

Research shows that casein protein effectively increases overnight muscle protein synthesis and aids recovery in athletes. While the evidence is moderate to high, further studies could explore long-term effects and optimal dosing.

Anaerobic power and strength
Soccer players · RCT
Moderate

Pre-sleep casein ingestion with probiotics improved anaerobic power and lower-body-specific strength and power performance.

Dose: 30000 mgDuration: Not specifiedTiming: Before sleep
Combined with probiotics for enhanced effect.
Functional recovery
Professional soccer players · RCT
Moderate

Presleep casein protein ingestion accelerated functional recovery in professional soccer players.

Dose: 30000 mgDuration: Not specifiedTiming: Before sleep
Post-prandial amino acid response
Healthy young men · RCT
Moderate

Different forms of casein protein modulated post-prandial plasma amino acid responses.

Dose: 40000 mgDuration: Single sessionForm: Micellar CaseinTiming: Post-exercise
Compared micellar, calcium, and sodium caseinate.
Overnight muscle protein synthesis
Healthy young men · RCT
High

Casein protein ingestion prior to sleep increased myofibrillar protein synthesis rates during overnight recovery.

Dose: 45000 mgDuration: Single nightForm: Micellar CaseinTiming: 30 min before sleep
Stacks containing Casein Protein
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Forms & usage
How to take it

Take 20-40 grams of casein protein 30 minutes before bed.

Micellar Casein
Slow-digesting form, ideal for pre-sleep consumption.
Calcium Caseinate
More soluble form, often used in protein blends.
Sodium Caseinate
Used in food processing, less common as a supplement.
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