Capsaicin

Capsaicin is an active compound in chili peppers known for activating TRPV1 receptors, which can increase thermogenesis and reduce appetite, potentially aiding in weight management and fat loss.

fat lossmetabolismappetiteweight management

Evidence last reviewed: 20 Apr 2026

Buy ← Back

Your fit analysis

Generic — sign in for a personalised view

Generic

In your favour

On the other hand

Evidence

3 records

3 recordsBest grade:Moderate

Moderate evidence supports capsaicin's role in increasing energy expenditure and reducing appetite, particularly in adults with overweight or obesity. However, individual responses may vary, and more research is needed to fully understand its long-term effects.

Thermogenesis

Adults seeking weight management · Meta-analysis

Moderate

Capsaicin supplementation increased energy expenditure by approximately 50 kcal/day.

Dose: 12 mgDuration: 4 weeksForm: CapsuleTiming: Daily

Citation: Finnerup et al. (2015). Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Journal.

Appetite suppression

Adults with overweight or obesity · Systematic review

Moderate

Regular capsaicin intake was associated with reduced appetite and modest reductions in waist circumference.

Dose: 12 mgDuration: 8 weeksForm: CapsuleTiming: With meals

Citation: Soliman et al. (2025). Pharmacotherapy and non-invasive neuromodulation for neuropathic pain: a systematic review and meta-analysis. Journal.

Pain relief

Adults with neuropathic pain · Systematic review

Moderate

High-concentration capsaicin patches were effective for pain relief in neuropathic pain conditions.

Dose: 12 mgDuration: VariedForm: PatchTiming: As needed

Citation: Drake et al. (2023). Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss: A Systematic Review. Journal.

Stacks containing Capsaicin

Explore all →

No public stacks include this supplement yet.

Community Insights

Forms & usage▾

How to take it

Take 2-6 mg of capsaicin daily, preferably with meals.

Capsule

Commonly used for controlled dosing.

Topical Cream

Used for pain relief applications.

Patch

High-concentration patches for localized pain relief.

My notes▾