Akkermansia Muciniphila
Akkermansia muciniphila is a mucin-degrading gut bacterium associated with metabolic health improvements, including enhanced insulin sensitivity & gut barrier function, particularly in overweight & obese individuals.
Evidence last reviewed: 05 Apr 2026
- •those with severe gut disorders
- •individuals on immunosuppressive therapy
- •pregnant or breastfeeding women
The evidence shows moderate effectiveness in improving muscle strength, reducing body weight, and enhancing insulin sensitivity in specific populations. However, more extensive studies are needed to confirm long-term benefits and effects in diverse groups.
Insulin sensitivityOverweight/obese insulin-resistant volunteers · RCTModerate
Supplementation with Akkermansia muciniphila improved insulin sensitivity & was well-tolerated.
Body weight & fat massOverweight/obese type 2 diabetes patients · RCTModerate
Akkermansia muciniphila supplementation led to significant reductions in body weight & fat mass in participants with low baseline levels of the bacterium.
Muscle strength & functionGeneral population · RCTModerate
Pasteurized Akkermansia muciniphila improved muscle strength & function.
Gut Health & Immunity
Akkermansia muciniphila & bifidobacterium longum are combined to support gut health & boost immunity. Akkermansia muciniphila is a beneficial gut bacterium that supports the gut lining, while bifidobacterium longum enhances gut microbiota diversity & immune function.
Forms & usage▾
Take 250-500 mg daily, preferably with meals.