Akkermansia Muciniphila
Akkermansia muciniphila is a mucin-degrading gut bacterium associated with metabolic health improvements, including enhanced insulin sensitivity & gut barrier function, particularly in overweight & obese individuals.
Evidence last reviewed: 05 Apr 2026
The evidence shows moderate effectiveness in improving muscle strength, reducing body weight, and enhancing insulin sensitivity in specific populations. However, more extensive studies are needed to confirm long-term benefits and effects in diverse groups.
Insulin sensitivityOverweight/obese insulin-resistant volunteers · RCTModerate
Supplementation with Akkermansia muciniphila improved insulin sensitivity & was well-tolerated.
Body weight & fat massOverweight/obese type 2 diabetes patients · RCTModerate
Akkermansia muciniphila supplementation led to significant reductions in body weight & fat mass in participants with low baseline levels of the bacterium.
Muscle strength & functionGeneral population · RCTModerate
Pasteurized Akkermansia muciniphila improved muscle strength & function.
Gut Health & Immunity
Akkermansia muciniphila & bifidobacterium longum are combined to support gut health & boost immunity. Akkermansia muciniphila is a beneficial gut bacterium that supports the gut lining, while bifidobacterium longum enhances gut microbiota diversity & immune function.
Forms & usage▾
Take 250-500 mg daily, preferably with meals.