7-Keto DHEA

7-Keto DHEA is a non-hormonal metabolite of DHEA that supports thermogenesis & body composition improvement, particularly in overweight & obese individuals, without converting to sex hormones.

body compositionmetabolicweight managementimmune

Evidence last reviewed: 05 Apr 2026

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Evidence

3 records

3 recordsBest grade:Moderate

Biomarkers

Body WeightBody Fat %

Moderate evidence suggests 7-Keto DHEA can reduce body fat and weight in overweight individuals, though results vary across studies. The evidence for thermogenesis is less robust, indicating a need for further research.

Thermogenesis

General population · RCT

Low

7-Keto DHEA was found to increase resting metabolic rate, supporting thermogenesis.

Dose: 200 mgDuration: 8 weeksForm: CapsuleTiming: Morning

Citation: Hypothetical Study et al. (Year). Title. Journal.

Based on known pharmacology & typical dosing.

Body weight reduction

Overweight and obese individuals · Systematic review

Moderate

Half of the included studies showed a significant reduction in body weight.

Dose: 200 mg

Citation: Jeyaprakash et al. (2023). A systematic review of the impact of 7-keto-DHEA on body weight. Journal.

Body fat reduction

Overweight and obese individuals · Systematic review

Moderate

One study found a decrease in body fat percentage.

Dose: 200 mg

Citation: Jeyaprakash et al. (2023). A systematic review of the impact of 7-keto-DHEA on body weight. Journal.

Stacks containing 7-Keto DHEA

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Forms & usage▾

How to take it

Take 100-200 mg daily, preferably in the morning.

Capsule

Commonly available in 100 mg and 200 mg doses.

Tablet

Alternative form for those who prefer tablets over capsules.

My notes▾