StackTerminal.Health

BETA

Yohimbine

Yohimbine is an alpha-2 adrenergic receptor antagonist derived from the bark of the Pausinystalia yohimbe tree, known for increasing norepinephrine release and facilitating fat mobilization, particularly effective in a fasted state. It is used for fat loss and has potential benefits for sexual health, but may cause side effects like anxiety and hypertension at higher doses.

fat-lossweight-lossstimulantsexual-health
Evidence last reviewed: 20 Apr 2026
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Biomarkers studied
Outcomes directly measured across the evidence records below
Hormonal
Testosterone
Metabolic
Body Fat %Body Weight
Cognitive
Anxiety
Evidence
3 records
Fat mobilization
AthletesSystematic review
PUBMEDModerate

Yohimbine is suggested to aid in fat mobilization, particularly in a fasted state, enhancing fat loss in athletes.

Dose: 20 mg
Erectile dysfunction
Men with erectile dysfunctionSystematic review and meta-analysis
PUBMEDModerate

Yohimbine has been shown to improve erectile function in men with erectile dysfunction.

Dose: 20 mg
Anxiety
General populationSystematic review
PUBMEDLow

Yohimbine may increase anxiety levels, particularly at higher doses.

Dose: 20 mg
Anxiety is a noted side effect of yohimbine.
Forms
HCl
Most common form used in supplements for fat loss and sexual health.
Bark extract
Traditional form, less standardized in dosing.

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