StackTerminal.Health

BETA

Vinpocetine

Vinpocetine is a semi-synthetic derivative of vincamine that may enhance cerebral blood flow & cognitive function, particularly in individuals with cognitive impairments or neurological conditions.

cognitivememoryneuroprotectioncardiovascular
Evidence last reviewed: 05 Apr 2026
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Biomarkers studied
Outcomes directly measured across the evidence records below
Cognitive
Cognitive FunctionNeuroprotection / NGF
Inflammation
TNF-α
Evidence
8 records
Cognitive function
Healthy adult volunteers • RCT
PUBMEDModerate

No significant cognitive benefits were observed in healthy volunteers.

Dose: 20 mgDuration: Single doseForm: Oral
Citation: Perng et al. (2018). The treatment of cognitive dysfunction in dementia: a multiple treatments meta-analysis. Psychopharmacology.
Neuroprotection
Acute ischemic stroke patients • Systematic review and Meta-analysis
PUBMEDModerate

Vinpocetine was well tolerated but not associated with positive cognitive effects in stroke patients.

Dose: 20 mg
Citation: Panda et al. (2022). Safety and Efficacy of Vinpocetine as a Neuroprotective Agent in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis. Neurocritical Care.
Higher dosages may be needed to assess efficacy.
Cognitive function
Patients with epilepsy • RCT
PUBMEDModerate

No significant cognitive benefits were observed in patients with epilepsy.

Dose: 20 mgDuration: One monthForm: Oral
Citation: Meador et al. (2021). Vinpocetine, cognition, and epilepsy. Epilepsy & Behavior.
Inflammation
Acute ischemic stroke patients • RCT
PUBMEDLow

Vinpocetine inhibits NF-κB-dependent inflammation in stroke patients.

Dose: 20 mg
Citation: Zhang et al. (2018). Vinpocetine Inhibits NF-κB-Dependent Inflammation in Acute Ischemic Stroke Patients. BMJ.
Inflammation
Acute ischemic stroke patients • RCT
PUBMEDLow

Vinpocetine inhibits NF-κB-dependent inflammation in stroke patients.

Dose: 20 mg
Citation: Zhang et al. (2018). Vinpocetine Inhibits NF-κB-Dependent Inflammation in Acute Ischemic Stroke Patients. BMJ.
Cognitive function
Healthy adult volunteers • RCT
PUBMEDModerate

No significant cognitive benefits were observed in healthy volunteers.

Dose: 20 mgDuration: Single doseForm: Oral
Citation: Perng et al. (2018). The treatment of cognitive dysfunction in dementia: a multiple treatments meta-analysis. Journal of Psychopharmacology.
Cognitive function
Patients with epilepsy • RCT
PUBMEDModerate

No significant cognitive benefits were observed in patients with epilepsy.

Dose: 20 mgDuration: One monthForm: Oral
Citation: Meador et al. (2021). Vinpocetine, cognition, and epilepsy. Epilepsy & Behavior.
Neuroprotection
Acute ischemic stroke patients • Systematic review and Meta-analysis
PUBMEDModerate

Vinpocetine was well tolerated but not associated with positive cognitive effects in stroke patients.

Dose: 20 mg
Citation: Panda et al. (2022). Safety and Efficacy of Vinpocetine as a Neuroprotective Agent in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis. Neurocritical Care.
Higher dosages may be needed to assess efficacy.
Forms
Tablet
Commonly available in 5 mg and 10 mg doses.
Capsule
Available in various dosages for oral administration.
Extended-release
Designed for prolonged effect, often used in clinical settings.

Stacks containing Vinpocetine

Public community stacks that include this ingredient.

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cognitivememoryfocus

Cognitive Memory Enhancement

by@athlete

Piracetam & vinpocetine are combined to enhance cognitive function & memory. Piracetam is known for its neuroprotective effects, while vinpocetine improves cerebral blood flow & cognitive performance.

Piracetam
2400mg
Vinpocetine
10mg
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