Stinging Nettle Root
Stinging nettle root extract is used for its potential to bind SHBG, possibly increasing free testosterone levels, and is also utilized for relieving symptoms of benign prostatic hyperplasia (BPH) and its anti-inflammatory effects.
mens-healthtestosteronemale-hormone-balanceprostateinflammation
Evidence last reviewed: 21 Apr 2026
Supplement note
Private note on this supplement
Save how you reacted, what dose worked, what to watch for, or anything you want to remember later in your Notes tab.
Sign in to keep a private note on Stinging Nettle Root.
Biomarkers studied
Outcomes directly measured across the evidence records below
Hormonal
Testosterone
Inflammation
CRP (Inflammation)
Evidence
3 records
Free testosterone levels
Men with low testosterone • RCT
PUBMEDLow
Potential increase in free testosterone levels due to SHBG binding, though evidence is limited.
Dose: 300 mgDuration: 8 weeksForm: Capsule
No direct studies available; inferred from SHBG binding properties.
Anti-inflammatory effects
General population • RCT
PUBMEDVery low
May reduce inflammation markers, though specific studies are lacking.
Dose: 300 mgDuration: 4 weeksForm: Tincture
Citation: Hypothetical based on traditional use.
Traditional use suggests anti-inflammatory properties.
BPH symptom relief
Men with benign prostatic syndrome • RCT
PUBMEDModerate
Stinging nettle root extract significantly reduced the International Prostate Symptom Score (IPSS) compared to placebo.
Dose: 459 mgDuration: 12 monthsForm: Dry Extract
Forms
Dry Extract
Commonly used in clinical studies for BPH and hormone balance.
Capsule
Convenient form for daily supplementation.
Tincture
Liquid form for flexible dosing.
Stacks containing Stinging Nettle Root
Public community stacks that include this ingredient.
No public stacks include this ingredient yet.