StackTerminal.Health

BETA

Soy Isoflavones

May reduce menopausal hot flash frequency/severity with small average effect; evidence is mixed & response varies.

womens-healthmenopauselongevitymetabolic-health
Evidence last reviewed: 04 Apr 2026
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Evidence
2 records
Hot flash frequency/severity
Peri-/postmenopausal womenEvidence synthesis / clinical summary
PUBMEDLow

Soy isoflavone supplements or soy protein may reduce hot flashes, but average effect is small & results are not fully consistent.

Dose: 50 mgDuration: 6–12 weeks (typical study windows)
Hot flash frequency reduction — quantitative meta-analysis
Peri-/postmenopausal womenMeta-analysis of RCTs
PUBMEDModerate

Model-based meta-analysis of 16 RCTs (~1,710 subjects) found soy isoflavones reduced hot flash frequency by a maximal 25.2% over placebo — a statistically real but modest effect compared to estradiol, with slow onset over several weeks.

Dose: 54 mgDuration: Varies (pooled across trials)
Forms
Capsule
Also achievable via soy foods

Stacks containing Soy Isoflavones

Public community stacks that include this ingredient.

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hormonalwomens-healthmenopause

Red clover isoflavones & soy isoflavones are combined to support hormonal balance & alleviate menopause symptoms. Both ingredients provide phytoestrogens that can help balance hormone levels & reduce menopause-related symptoms.

Red Clover Isoflavones
40mg
Soy Isoflavones
40mg
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