StackTerminal.Health

Red Clover Isoflavones

Studied for menopause symptoms; findings are inconsistent and some studies have higher risk of bias.

womens-healthmenopauselongevity
Dosing model
FLATFixed dose (no body-weight scaling).
Min dose
40 mg
Max dose
80 mg
Rounding
10 mg

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Evidence
2 records
Menopausal hot flashes
Postmenopausal womenEvidence summary
Very low

Trials and reviews show inconsistent effects on hot flashes; uncertainty remains due to study quality and heterogeneity.

Dose: 80 mg Duration: 8–12 weeks (typical study windows)
Hot flash frequency — systematic review and meta-analysis
Peri- and postmenopausal womenSystematic review and meta-analysis of RCTs
Low

Systematic review found red clover may reduce hot flash frequency (approaching statistical significance), with greater effect in women with ≥5 flashes/day. Effect not sustained at 12 months; vaginal atrophy symptoms improved with 80 mg/day. Evidence quality is limited by heterogeneity.

Dose: 80 mg Duration: 8–12 weeks
Forms
Capsule
Standardization varies across products