StackTerminal.Health

BETA

Quercetin

Flavonoid with anti-inflammatory & senolytic properties; often combined with EGCG or fisetin.

longevityantioxidantimmunerecovery

Evidence last reviewed: 04 Apr 2026

Bottom line

Quercetin is a flavonoid with anti-inflammatory and potential senolytic effects. It may offer small improvements in endurance but has notable drug interactions.

Safety & trade-offs
Known concerns, timing, & interactions
Interaction

Inhibits CYP3A4 and CYP2C9 — interacts with cyclosporine, warfarin, and other drugs

Interaction

May reduce absorption of some antibiotics — separate by at least 2 hours

High  Moderate   Low / note

Summarized study outcomes with population, design, grade, and effect data.

1 recordBest grade:Moderate
Endurance performance / inflammation

Meta-analyses show moderate evidence for quercetin's benefits in endurance performance and inflammation reduction, particularly in athletes and older adults. However, the effects are small and further research is needed to fully understand its senolytic properties.

Endurance performance / inflammation
Athletes; older adults · Meta-analyses
Moderate

Small but consistent improvements in endurance; anti-inflammatory signals; senolytic effects under study.

Dose: 500 mgDuration: 2–8 weeks
Often paired with vitamin C to enhance bioavailability.

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