StackTerminal.Health

BETA
Research compound

This compound is primarily studied in research/clinical settings & may not be widely available as a regulated over-the-counter supplement. Information is provided for educational purposes only — not as a recommendation to use. See our Safety page.

PT-141 (Bremelanotide)

PT-141, also known as Bremelanotide, is a melanocortin receptor agonist approved for treating hypoactive sexual desire disorder in premenopausal women, enhancing sexual desire and satisfaction.

sexual-healthlibidomoodarousal
Evidence last reviewed: 19 Apr 2026
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Evidence
4 records
Safety profile
Premenopausal women with hypoactive sexual desire disorderSystematic review
PUBMEDHigh

The most common adverse events were nausea, flushing, headache, and injection site reactions.

Dose: 1 mgDuration: Up to 18 months
Adverse event-induced study discontinuation
Premenopausal women with hypoactive sexual desire disorderMeta-analysis
PUBMEDModerate

Adverse event-induced study discontinuation was significantly higher in the bremelanotide group compared to placebo.

Dose: 1 mg
Sexual satisfaction
Premenopausal women with hypoactive sexual desire disorderRCT
PUBMEDHigh

Bremelanotide improved sexual satisfaction and related distress in premenopausal women.

Dose: 1 mgDuration: 24 weeksForm: Subcutaneous InjectionTiming: As needed
Sexual desire
Premenopausal women with hypoactive sexual desire disorderRCT
PUBMEDHigh

Bremelanotide significantly increased sexual desire and reduced distress related to low sexual desire compared to placebo.

Dose: 1 mgDuration: 24 weeksForm: Subcutaneous InjectionTiming: As needed
Forms
Subcutaneous Injection
Administered as needed, typically 1.75 mg per dose.

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