StackTerminal.Health

BETA

Probiotics (General)

Probiotics are live microorganisms that provide health benefits, particularly for gut health, immune function, & potentially mood & metabolic health.

gut-healthimmunemental-healthmetabolic

Evidence last reviewed: 05 Apr 2026

Bottom line

Probiotics are live microorganisms that can support gut health and may help with mood and metabolic issues. They are generally safe with moderate evidence backing their benefits for specific conditions.

Summarized study outcomes with population, design, grade, and effect data.

5 recordsBest grade:Moderate
depressionanxietyacute infectious diarrhoeairritable bowel syndromeinsulin resistance

Moderate evidence suggests probiotics can help with depression, anxiety, IBS, and acute diarrhoea. However, the evidence for insulin resistance in PCOS is less robust. Overall, while beneficial for many, individual responses may vary.

Biomarkers studied
Metabolic
Insulin Sensitivity
Cognitive
Mood / WellbeingAnxiety
Gut
Gut Microbiome
depression
Individuals with depression · Meta-analysis
Moderate
anxiety
Individuals with anxiety · Meta-analysis
Moderate
acute infectious diarrhoea
Individuals with acute infectious diarrhoea · Systematic review
Moderate

Probiotics may be effective in reducing the duration of acute infectious diarrhoea.

Dose:
irritable bowel syndrome
Individuals with IBS · Systematic review
Moderate

Probiotics may provide benefits for managing symptoms of irritable bowel syndrome.

Dose:
insulin resistance
Women with Polycystic Ovary Syndrome (PCOS) · Systematic review
Low

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