Probiotic Multi-Strain

Multi-strain probiotic formulations supporting gut health, immune function, and respiratory infection prevention.

gut

Dosing model

FLATFixed dose (no body-weight scaling).

Min dose

0 mg

Max dose

0 mg

Rounding

—

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Evidence

3 records

Gut microbiome diversity and general gut health

Healthy adults • Randomized controlled trial

Moderate

Multi-strain probiotic supplementation improved gut microbiome diversity and markers of gut health vs placebo.

Dose: —

Citation: Goodman C, et al. 2021.

Reduction in incidence and duration of acute upper respiratory tract infections

Children and adults across 23 RCTs (n=6,950) • Cochrane systematic review and meta-analysis of RCTs

Moderate

Probiotic supplementation reduced the number of participants experiencing at least one URTI by 24% (RR 0.76), reduced recurrent URTIs (≥3 episodes) by 41% (RR 0.59), shortened mean infection duration by ~1.2 days, and decreased antibiotic prescriptions by 42% (RR 0.58) vs placebo. Evidence certainty: low to moderate.

Dose: —

Citation: Zhao Y, Dong BR, Hao Q. Probiotics for preventing acute upper respiratory tract infections. Cochrane Database Syst Rev. 2022;8(8):CD006895.

Cochrane review; effects consistent across strains though specific strain superiority not established.

Global symptom relief in irritable bowel syndrome (IBS)

IBS patients across 43 RCTs (n=5,531) • Systematic review and network meta-analysis of RCTs

Moderate

Probiotics improved IBS global symptom relief, abdominal pain, bloating, and straining vs placebo; B. coagulans showed the highest probability of being optimal for symptom relief and pain; treatment duration ≥8 weeks produced the best outcomes.

Dose: —

Citation: Zhang T, Zhang C, Zhang J, Sun F, Duan L. Efficacy of Probiotics for Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis. Front Cell Infect Microbiol. 2022;12:859967.

Network meta-analysis allows strain-level comparisons; dose had no significant effect on outcomes.

Forms

Capsule

Report CFU and strains (not mg)