StackTerminal.Health

BETA

Probiotic Multi-Strain

Multi-strain probiotic formulations supporting gut health, immune function, & respiratory infection prevention.

gut
Evidence last reviewed: 04 Apr 2026
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Biomarkers studied
Outcomes directly measured across the evidence records below
Gut
Gut MicrobiomeGut Permeability
Immune
Immune Function
Evidence
3 records
Global symptom relief in irritable bowel syndrome (IBS)
IBS patients across 43 RCTs (n=5,531)Systematic review and network meta-analysis of RCTs
PUBMEDModerate

Probiotics improved IBS global symptom relief, abdominal pain, bloating, & straining vs placebo; B. coagulans showed the highest probability of being optimal for symptom relief & pain; treatment duration ≥8 weeks produced the best outcomes.

Dose:
Network meta-analysis allows strain-level comparisons; dose had no significant effect on outcomes.
Gut microbiome diversity & general gut health
Healthy adultsRandomized controlled trial
PUBMEDModerate

Multi-strain probiotic supplementation improved gut microbiome diversity & markers of gut health vs placebo.

Dose:
Reduction in incidence & duration of acute upper respiratory tract infections
Children and adults across 23 RCTs (n=6,950)Cochrane systematic review and meta-analysis of RCTs
COCHRANEModerate

Probiotic supplementation reduced the number of participants experiencing at least one URTI by 24% (RR 0.76), reduced recurrent URTIs (≥3 episodes) by 41% (RR 0.59), shortened mean infection duration by ~1.2 days, & decreased antibiotic prescriptions by 42% (RR 0.58) vs placebo. Evidence certainty: low to moderate.

Dose:
Cochrane review; effects consistent across strains though specific strain superiority not established.
Forms
Capsule
Report CFU and strains (not mg)

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