Pramiracetam

Pramiracetam is a potent nootropic that enhances high-affinity choline uptake, potentially improving long-term memory formation & attention, particularly in individuals with cognitive impairment.

cognitivememoryfocusneuroprotection

Evidence last reviewed: 05 Apr 2026

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Biomarkers studied

Outcomes directly measured across the evidence records below

Cognitive

Cognitive FunctionMemory

Evidence

2 records

Pharmacokinetics

Normal male volunteers • RCT

PUBMEDModerate

Pramiracetam showed a peak plasma concentration between 2 to 3 hours post-administration with a half-life of 4.5 to 6.5 hours.

Dose: 400 mgTiming: After an overnight fast

Citation: Chang et al. (1985). Pharmacokinetics of oral pramiracetam in normal volunteers. Journal of Clinical Pharmacology.

Cognitive enhancement

Individuals with cognitive impairment • Systematic review

PUBMEDLow

Pramiracetam is suggested to enhance cognition & memory, though evidence is limited & primarily based on pharmacological properties.

Dose: 400 mg

Citation: Malykh et al. (2010). Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. CNS Drugs.

The review discusses pramiracetam among other racetams, highlighting its potential but limited clinical evidence.

Forms

Capsule

Commonly available in 400 mg capsules.

Powder

Can be mixed with liquids for flexible dosing.

Stacks containing Pramiracetam

Public community stacks that include this ingredient.

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cognitivemoodfocus

Cognitive & Mood Support

by@athlete

Pramiracetam & phenylalanine are combined to support cognitive function & mood. Pramiracetam enhances memory & cognitive performance, while phenylalanine supports mood & cognitive function by acting as a precursor to neurotransmitters.

Pramiracetam

400mg

L-Phenylalanine

500mg

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