StackTerminal.Health

BETA
Research compound

This compound is primarily studied in research/clinical settings & may not be widely available as a regulated over-the-counter supplement. Information is provided for educational purposes only — not as a recommendation to use. See our Safety page.

Paxil (Paroxetine)

Paxil is a potent SSRI used to treat depression, social anxiety, PTSD, OCD, & panic disorder, with notable withdrawal challenges.

mental-healthdepressionanxietysocial-anxiety
Evidence last reviewed: 05 Apr 2026
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Evidence
5 records
Major depressive disorder maintenance
Adults with major depressive disorderSystematic review
PUBMEDHigh

Paroxetine was effective in reducing the 6-month relapse rate in major depressive disorder.

Dose: 20 mgDuration: 6 months
Dose equivalence
General populationRCT
PUBMEDModerate

Paroxetine dosage equivalent to fluoxetine 40mg/day was found to be 34mg/day.

Dose: 34 mg
Poststroke depression
Adults with poststroke depressionMeta-analysis
PUBMEDModerate

Paroxetine was found to be effective for poststroke depression.

Dose: 20 mg
Premature ejaculation
Men with premature ejaculationSystematic review
PUBMEDModerate

Paroxetine was effective in managing premature ejaculation.

Dose: 20 mgTiming: On-demand
Generalized anxiety disorder
General populationCase series
PUBMEDLow

Paroxetine is widely used for generalized anxiety disorder, though concerns about suicidality in younger patients exist.

Dose: 20 mg
Concerns about suicidality risk in younger patients.
Forms
Tablet
Commonly prescribed form for oral administration.
Suspension
Liquid form for those who have difficulty swallowing tablets.

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