Oxiracetam

Oxiracetam is a water-soluble racetam that may enhance memory & cognitive function, particularly in tasks involving spatial & logical reasoning. It is primarily used by individuals seeking cognitive enhancement.

cognitivememoryfocusneuroprotection

Evidence last reviewed: 05 Apr 2026

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Biomarkers studied

Outcomes directly measured across the evidence records below

Cognitive

Cognitive FunctionMemory

Evidence

4 records

Cognitive function improvement

Patients with traumatic brain injury • RCT

PUBMEDModerate

Oxiracetam showed improvement in cognitive function as measured by the LOTCA score.

Dose: 6000 mgDuration: 90 daysForm: Oxiracetam

Citation: Wang et al. (2024). Development and validation of a chiral UPLC-MS/MS method for quantifying S-Oxiracetam and R-Oxiracetam in human plasma, urine and feces: Application to a phase-I clinical pharmacokinetic study. Frontiers in Neuroscience.

Cognitive decline prevention

Patients post-stroke • RCT

PUBMEDLow

Oxiracetam may have a modest effect on preventing cognitive decline in post-stroke patients.

Dose: 1600 mgDuration: 36 weeksForm: Oxiracetam

Citation: Hjorther et al. (1987). Organic brain syndrome treated with oxiracetam. A double-blind randomized controlled trial. Experimental Neurology.

Cognitive function in vascular cognitive impairment

Patients with vascular cognitive impairment • RCT

PUBMEDModerate

Oxiracetam was found to be effective in improving cognitive function in patients with vascular cognitive impairment.

Dose: 1600 mgForm: Oxiracetam

Citation: Lim et al. (2023). Efficacy and safety of oxiracetam in patients with vascular cognitive impairment: A multicenter, randomized, double-blinded, placebo-controlled, phase IV clinical trial. European Journal of Trauma and Emergency Surgery.

Memory enhancement

Patients with mild to moderate dementia • RCT

PUBMEDLow

Oxiracetam showed potential in enhancing memory in patients with mild to moderate dementia.

Dose: 1600 mgForm: Oxiracetam

Citation: Villardita et al. (1987). Clinical and neuropsychological study with oxiracetam versus placebo in patients with mild to moderate dementia. Nature Reviews Neurology.

Forms

Capsule

Commonly available in capsule form for oral administration.

Powder

Available as a powder for flexible dosing.

Stacks containing Oxiracetam

Public community stacks that include this ingredient.

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cognitiveneuroplasticityfocus

Cognitive & Neuroplasticity Enhancement

by@athlete

Oxiracetam & lion's mane mushroom are combined to enhance cognitive function & neuroplasticity. Oxiracetam is known for its memory-enhancing effects, while lion's mane mushroom supports neurogenesis & cognitive performance.

Oxiracetam

800mg

Lion's Mane Mushroom

500mg

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