StackTerminal.Health

BETA
Research compound

This compound is primarily studied in research/clinical settings & may not be widely available as a regulated over-the-counter supplement. Information is provided for educational purposes only — not as a recommendation to use. See our Safety page.

Naltrexone

Naltrexone is an opioid receptor antagonist primarily used for treating alcohol & opioid use disorders. It is also being studied in low doses for autoimmune conditions & chronic pain disorders like fibromyalgia.

addictionimmuneanti-inflammatorymental-health
Evidence last reviewed: 05 Apr 2026
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Evidence
4 records
Impulse control disorders
Adults with impulse control disordersSystematic review
PUBMEDModerate

Naltrexone was evaluated for impulse control disorders with moderate strength of evidence for benefit.

Dose: 50 mg
Alcohol use disorder
Adults with alcohol use disorderSystematic review and Meta-analysis
PUBMEDHigh

Oral naltrexone at 50 mg/day is associated with lower rates of return to heavy drinking.

Dose: 50 mgForm: Oral tablet
Alcohol use disorder
Adults with alcohol use disorderSystematic review and Meta-analysis
PUBMEDHigh

Supports the use of oral naltrexone at 50 mg/day as a first-line pharmacotherapy for alcohol use disorder.

Dose: 50 mgForm: Oral tablet
Binge-eating disorder
Adults with binge-eating disorderRCT
PUBMEDLow

Naltrexone/bupropion was studied for binge-eating disorder, with primary outcomes focused on alcohol consumption.

Dose: 50 mg
The study primarily focused on alcohol consumption rather than binge-eating outcomes.
Forms
Oral tablet
Commonly used for alcohol and opioid use disorder.
Injectable
Used for extended-release formulations.

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