Lactobacillus crispatus
Lactobacillus crispatus is a probiotic that helps maintain a healthy vaginal microbiome, primarily used to prevent bacterial vaginosis and support vaginal health in women.
vaginal-healthgut-healthwomens-healthimmune-support
Evidence last reviewed: 20 Apr 2026
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Evidence
3 records
Recurrence of bacterial vaginosis
Women aged 18 to 45 with a history of bacterial vaginosis • RCT
PUBMEDHigh
Lactobacillus crispatus CTV-05 significantly reduced the recurrence of bacterial vaginosis compared to placebo.
Dose: —Duration: 11 weeksForm: Lactin-V
Vaginal microbiome restoration
Women aged 18 to 45 post-metronidazole treatment for bacterial vaginosis • RCT
PUBMEDModerate
Lactobacillus crispatus CTV-05 was detected in 79% of participants, indicating successful colonization and microbiome restoration.
Dose: —Duration: 24 weeksForm: Lactin-V
Prevention of urinary tract infections
Women with a history of bacterial vaginosis • Systematic review
PUBMEDLow
Lactobacillus crispatus suppositories may help reduce the incidence of urinary tract infections.
Dose: —Form: Vaginal suppository
Forms
Vaginal suppository
Direct application to the vaginal area for targeted microbiome support.
Oral capsule
Systemic probiotic support, though less direct for vaginal health.
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