StackTerminal.Health

BETA
Research compound

This compound is primarily studied in research/clinical settings & may not be widely available as a regulated over-the-counter supplement. Information is provided for educational purposes only — not as a recommendation to use. See our Safety page.

KPV

Tripeptide (α-MSH fragment) studied mainly in gut inflammation models; evidence is largely preclinical.

goal:gut-digestiongoal:gut-healthgoal:microbiomeconstraint:not-drug-test-safeevidence:lowstudy:mechanistic-animalpop:other-unclearform:other
Evidence last reviewed: 04 Apr 2026
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Evidence
3 records
Colitis-associated cancer prevention (preclinical)
Mouse models (PepT1-expressing)Preclinical (animal)
PUBMEDLow

KPV transported via PepT1 reduced colitis severity & prevented carcinogenesis in murine colitis-associated cancer models; no human trials identified.

Dose:
Colitis severity reduction
Mouse colitis models + cellular modelsPreclinical (cell + mouse)
PUBMEDLow

KPV showed anti-inflammatory effects mediated by PepT1 transport in intestinal epithelial/immune cells & reduced inflammation in mouse colitis models.

Dose: Duration: Preclinical protocol (see paper)
Targeted KPV delivery for ulcerative colitis (preclinical)
Mouse ulcerative colitis models (DSS and TNBS)Preclinical (animal + in vitro)
PUBMEDLow

Hyaluronic acid-functionalized nanoparticles loaded with KPV showed targeted delivery to colonic epithelial cells & macrophages, reducing inflammation in murine UC models; translational relevance to humans is not established.

Dose: Form: Hyaluronic acid-functionalized nanoparticles
Forms
Other
Research material (vendor listing)

Stacks containing KPV

Public community stacks that include this ingredient.

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gutdigestionresearch-only

Groups gut-inflammation oriented peptides (mostly studied in preclinical colitis/inflammation models).

KPV
1mg
BPC-157
1mg
Magnesium (Glycinate)
400mg
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