StackTerminal.Health

BETA

Iron (Ferrous Bisglycinate)

Ferrous bisglycinate is an amino acid chelate form of iron with superior bioavailability & gastrointestinal tolerability compared to traditional iron salts; it is the first-line choice for iron deficiency anemia supplementation, particularly in pregnancy.

anemiaenergywomens-healthmetabolicoxygen-transport
Evidence last reviewed: 04 Apr 2026
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Biomarkers studied
Outcomes directly measured across the evidence records below
Bloodwork
Ferritin / Iron
Evidence
2 records
Hemoglobin & ferritin concentrations in iron deficiency
Pregnant women and children with iron deficiencysystematic review and meta-analysis of RCTs
PUBMEDModerate

Meta-analysis of 17 RCTs found ferrous bisglycinate produced significantly higher hemoglobin concentrations & fewer gastrointestinal adverse events compared to other iron supplements in pregnant women; ferritin showed a non-significant trend toward improvement; no clear advantage was demonstrated in children.

Dose: 25 mgDuration: ≥4 weeksForm: Bisglycinate
Iron absorption & bioavailability compared to ferrous sulfate
Adults assessed in absorption studycontrolled bioavailability study
PUBMEDModerate

A controlled human absorption study found geometric mean iron absorption from ferrous bisglycinate (6.0%) was approximately 4-fold higher than ferrous sulfate (1.7%) in whole-maize meal; absorption from bisglycinate was regulated by iron status & did not exchange with non-heme food iron, indicating a protected chelate pathway.

Dose: 30 mgForm: Bisglycinate
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