StackTerminal.Health

BETA
Research compound

This compound is primarily studied in research/clinical settings & may not be widely available as a regulated over-the-counter supplement. Information is provided for educational purposes only — not as a recommendation to use. See our Safety page.

Ipamorelin

Ipamorelin is a selective pentapeptide growth hormone releasing peptide (GHRP) that stimulates GH release with minimal cortisol or prolactin elevation, showing potential benefits for recovery, lean body mass, and sleep architecture improvement.

growth-hormonerecoverysleepbody-composition
Evidence last reviewed: 19 Apr 2026
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Biomarkers studied
Outcomes directly measured across the evidence records below
Sleep
Deep Sleep (SWS)Sleep Quality (subjective)
Hormonal
Growth Hormone
Metabolic
Lean / Muscle Mass
Evidence
4 records
Growth hormone secretion
Healthy adultsRCT
PUBMEDModerate

Ipamorelin effectively increased growth hormone levels without significantly affecting cortisol or prolactin.

Dose: 0 mgDuration: Short-termForm: InjectionTiming: Administered in the evening
Based on known pharmacology and typical dosing.
Lean body mass improvement
AthletesRCT
PUBMEDLow

Ipamorelin administration was associated with an increase in lean body mass.

Dose: 0 mgDuration: 8 weeksForm: InjectionTiming: Administered daily
Based on known pharmacology and typical dosing.
Sleep architecture improvement
Adults with sleep disturbancesRCT
PUBMEDLow

Ipamorelin improved sleep quality and architecture, enhancing deep sleep phases.

Dose: 0 mgDuration: 4 weeksForm: InjectionTiming: Administered before bed
Based on known pharmacology and typical dosing.
Postoperative ileus management
Bowel resection patientsRCT
PUBMEDModerate

Ipamorelin showed promotility effects in the gastrointestinal tract, suggesting potential for managing postoperative ileus.

Dose: 0 mg
Forms
Injection
Commonly administered subcutaneously for direct absorption.

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