StackTerminal.Health

BETA
Research compound

This compound is primarily studied in research/clinical settings & may not be widely available as a regulated over-the-counter supplement. Information is provided for educational purposes only — not as a recommendation to use. See our Safety page.

Ibogaine

Ibogaine is an alkaloid derived from the African shrub Tabernanthe iboga, known for its potential to interrupt opioid, stimulant, & alcohol dependence with a single administration. It is primarily used in addiction treatment, although its safety profile requires careful consideration.

addictionmental-healthneuroplasticity
Evidence last reviewed: 05 Apr 2026
Supplement note
Private note on this supplement

Save how you reacted, what dose worked, what to watch for, or anything you want to remember later in your Notes tab.

Sign in to keep a private note on Ibogaine.
Evidence
4 records
Substance use disorder treatment
Individuals with substance use disordersSystematic review
PUBMEDLow

Ibogaine is suggested to be effective in reducing withdrawal symptoms & cravings in substance use disorders.

Dose: 1000 mg
Includes data from various study designs, highlighting potential benefits & risks.
Addiction treatment efficacy
Individuals with substance use disordersSystematic review
PUBMEDLow

Ibogaine shows potential as a rapid-onset therapy for addiction, though rigorous study designs are needed for safe application.

Dose: 1000 mg
Calls for more controlled studies to establish safety & efficacy.
Safety profile
General population using ibogaineSystematic review
PUBMEDLow

The review highlights severe medical complications & deaths associated with ibogaine, linked to neuro- & cardiotoxic effects.

Dose: 1000 mg
Emphasizes the need for controlled settings to mitigate risks.
Neurotoxicity assessment
Individuals using ibogaine for drug abuse treatmentCase series
PUBMEDVery low

Ibogaine has hallucinogenic & psychostimulant effects, with potential neurotoxic risks.

Dose: 1000 mg
Highlights the need for controlled studies to assess safety.
Forms
Ibogaine Hydrochloride
Commonly used in clinical settings for addiction treatment.
Iboga Root Bark
Traditional form, less standardized in dosing.

Stacks containing Ibogaine

Public community stacks that include this ingredient.

Explore all stacks →
No public stacks include this ingredient yet.