Glutamine
Glutamine is the most abundant amino acid in the body & the primary fuel for enterocytes & immune cells; evidence supports its role in preserving gut barrier integrity under stress & dramatically reducing symptoms in post-infectious irritable bowel syndrome.
Save how you reacted, what dose worked, what to watch for, or anything you want to remember later in your Notes tab.
A randomized placebo-controlled trial (n=106) found 79.6% of the glutamine group versus 5.8% of placebo achieved the primary endpoint (≥50-point reduction in IBS Severity Scoring System), a 14-fold difference; glutamine also reduced bowel movement frequency & improved intestinal permeability measures.
Meta-analysis of 10 clinical trials (n=352) found that overall glutamine supplementation did not significantly reduce intestinal permeability, but subgroup analysis showed significant benefit at doses >30 g/day for durations under 2 weeks, suggesting dose-dependent effects.
Stacks containing Glutamine
Public community stacks that include this ingredient.