StackTerminal.Health

BETA
Research compound

This compound is primarily studied in research/clinical settings & may not be widely available as a regulated over-the-counter supplement. Information is provided for educational purposes only — not as a recommendation to use. See our Safety page.

Effexor (Venlafaxine)

Effexor is an SNRI used to treat depression, generalized anxiety disorder, social anxiety, & panic disorder. It is known for its dual action on norepinephrine & serotonin reuptake, which may offer superior efficacy in severe depression compared to SSRIs.

mental-healthdepressionanxietypain
Evidence last reviewed: 05 Apr 2026
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Biomarkers studied
Outcomes directly measured across the evidence records below
Cognitive
Mood / WellbeingAnxiety
Evidence
5 records
Depression relapse rate
Adults with major depressive disorderSystematic review
PUBMEDHigh

Venlafaxine was effective in reducing the 6-month relapse rate in patients with major depressive disorder.

Dose: 150 mgDuration: 6 months
Optimal dose for major depression
Adults with major depressionSystematic review
PUBMEDModerate

The study aimed to determine the optimal dose of venlafaxine for treating major depression.

Dose: 150 mg
Efficacy in panic disorder
Adults with panic disorderMeta-analysis
PUBMEDHigh

Venlafaxine is effective in treating panic disorder, achieving a balance between efficacy & tolerability.

Dose: 150 mg
Adverse events risk
Adults with major depressive disorderSystematic review
PUBMEDModerate

Venlafaxine is associated with a risk of adverse events, which should be considered in treatment planning.

Dose: 150 mg
Withdrawal symptoms
Adults discontinuing venlafaxineSystematic review
PUBMEDModerate

Withdrawal symptoms are common after discontinuation of venlafaxine, with symptoms appearing within a few days & lasting a few weeks.

Dose: 150 mg
Forms
Tablet
Commonly prescribed form for oral administration.
Extended-release capsule
Allows for once-daily dosing.

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