Capsaicin
Capsaicin is an active compound in chili peppers known for activating TRPV1 receptors, which can increase thermogenesis and reduce appetite, potentially aiding in weight management and fat loss.
fat-lossmetabolismappetiteweight-management
Evidence last reviewed: 20 Apr 2026
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Evidence
3 records
Thermogenesis
Adults seeking weight management • Meta-analysis
PUBMEDModerate
Capsaicin supplementation increased energy expenditure by approximately 50 kcal/day.
Dose: 12 mgDuration: 4 weeksForm: CapsuleTiming: Daily
Appetite suppression
Adults with overweight or obesity • Systematic review
PUBMEDModerate
Regular capsaicin intake was associated with reduced appetite and modest reductions in waist circumference.
Dose: 12 mgDuration: 8 weeksForm: CapsuleTiming: With meals
Pain relief
Adults with neuropathic pain • Systematic review
PUBMEDModerate
High-concentration capsaicin patches were effective for pain relief in neuropathic pain conditions.
Dose: 12 mgDuration: VariedForm: PatchTiming: As needed
Forms
Capsule
Commonly used for controlled dosing.
Topical Cream
Used for pain relief applications.
Patch
High-concentration patches for localized pain relief.
Stacks containing Capsaicin
Public community stacks that include this ingredient.
No public stacks include this ingredient yet.