StackTerminal.Health

BETA
Research / clinical compound

Not a routine supplement — not recommended for self-directed use.

Information here is educational only, not a recommendation to use. See our Safety page.

Adderall (Amphetamine Salts)

Adderall is a mixed amphetamine salt formulation used primarily for treating ADHD & narcolepsy, enhancing attention & executive function through dopamine & norepinephrine modulation.

focusattentioncognitiveadhd

Evidence last reviewed: 05 Apr 2026

← Back
Bottom line

Adderall is a prescription medication primarily for ADHD and narcolepsy. It effectively enhances attention and executive function but carries potential risks, especially in certain populations.

Summarized study outcomes with population, design, grade, and effect data.

4 recordsBest grade:High
Attention & executive functionCardiovascular effectsSubstance use disorder treatmentCognitive impairment in bipolar disorder

Evidence is from research or clinical settings — does not imply safety outside supervised contexts.

Adderall has strong evidence supporting its efficacy in improving ADHD symptoms, with moderate support for its use in bipolar disorder and cocaine use disorder. However, it may cause cardiovascular effects and serious side effects in some individuals, highlighting the need for careful monitoring.

Biomarkers studied
Cardiovascular
Blood PressureResting Heart Rate
Cognitive
Focus / AttentionCognitive Function
Attention & executive function
Adults with ADHD · Systematic review
High

Amphetamines, including mixed amphetamine salts, show robust evidence of efficacy in improving ADHD symptoms.

Dose in study: 20 mg(trial dose)
Citation: Elliott et al. (2020). Pharmacologic treatment of attention deficit hyperactivity disorder in adults: A systematic review and network meta-analysis. PLoS One.
Cardiovascular effects
Adults using ADHD therapies · Systematic review
Low

ADHD medications, including amphetamines, cause modest elevations in resting heart rate & blood pressure.

Dose in study: 20 mg(trial dose)
Citation: Peruzzolo et al. (2013). Pharmacotherapy of bipolar disorder in children and adolescents: an update. Medical Decision Making.
Long-term safety data is limited.
Substance use disorder treatment
Adults with cocaine use disorder · Systematic review
Moderate

Prescription amphetamines were effective in promoting sustained abstinence in patients with cocaine use disorder.

Dose in study: 20 mg(trial dose)
Citation: Ahmann et al. (2001). Placebo-controlled evaluation of amphetamine mixture-dextroamphetamine salts and amphetamine salts (Adderall): efficacy rate and side effects. Clinical Drug Investigation.
Cognitive impairment in bipolar disorder
Adults with ADHD and bipolar disorder · Systematic review
Moderate

Amphetamines have robust evidence of efficacy for ADHD symptoms in bipolar disorder, but may cause serious side effects.

Dose in study: 20 mg(trial dose)
Citation: Miskowiak et al. (2024). Efficacy and safety of established and off-label ADHD drug therapies for cognitive impairment or attention-deficit hyperactivity disorder symptoms in bipolar disorder: A systematic review by the ISBD Targeting Cognition Task Force. Annals of Internal Medicine.
Potential for serious side effects like psychotic symptoms.

Stacks containing Adderall (Amphetamine Salts)

Public community stacks that include this ingredient.

Explore all →
cognitiveenergyfocus

Cognitive & Energy Support

by@athlete

Adderall & acetyl-l-carnitine are combined to support cognitive function & enhance energy levels. Adderall is a stimulant that improves focus & cognitive performance, while acetyl-l-carnitine supports mitochondrial function & energy production.

Adderall (Amphetamine Salts)
10mg
Acetyl-L-Carnitine
1000mg
New
View