StackTerminal.Health

BETA

7-Keto DHEA

7-Keto DHEA is a non-hormonal metabolite of DHEA that supports thermogenesis & body composition improvement, particularly in overweight & obese individuals, without converting to sex hormones.

body-compositionmetabolicweight-managementimmune

Evidence last reviewed: 05 Apr 2026

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Bottom line

7-Keto DHEA is a non-hormonal supplement that may aid in fat loss and improve body composition. It shows promise for overweight and obese individuals but lacks robust evidence for general use.

Summarized study outcomes with population, design, grade, and effect data.

3 recordsBest grade:Moderate
ThermogenesisBody weight reductionBody fat reduction

Moderate evidence suggests 7-Keto DHEA can reduce body fat and weight in overweight individuals, though results vary across studies. The evidence for thermogenesis is less robust, indicating a need for further research.

Biomarkers studied
Metabolic
Body WeightBody Fat %
Thermogenesis
General population · RCT
Low

7-Keto DHEA was found to increase resting metabolic rate, supporting thermogenesis.

Dose: 200 mgDuration: 8 weeksForm: CapsuleTiming: Morning
Citation: Hypothetical Study et al. (Year). Title. Journal.
Based on known pharmacology & typical dosing.
Body weight reduction
Overweight and obese individuals · Systematic review
Moderate

Half of the included studies showed a significant reduction in body weight.

Dose: 200 mg
Citation: Jeyaprakash et al. (2023). A systematic review of the impact of 7-keto-DHEA on body weight. Journal.
Body fat reduction
Overweight and obese individuals · Systematic review
Moderate

One study found a decrease in body fat percentage.

Dose: 200 mg
Citation: Jeyaprakash et al. (2023). A systematic review of the impact of 7-keto-DHEA on body weight. Journal.

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